However, unpredictable things often happen in these Pac-12 after dark games, so which sides should you favor with Week 4 college football bets? Before locking in any college football picks for Week 4 of the 2023 season, be sure to see the college football betting guide from legendary Vegas handicapper Bruce Marshall.įor years Vegas-based Marshall was synonymous with The Gold Sheet, the famed sports betting newsletter. Given the large Week 4 college football spreads for these contests, Williams and Penix could pile up stats that further separate themselves in the Heisman race. Meanwhile, Penix has the Huskies favored by 20.5 points, per the Week 4 college football lines, after he tossed for 375 yards and four touchdowns in the first half of his last game. The Trojans are massive 34.5-point favorites in the SportsLine consensus Week 4 college football odds, marking the fourth straight game Williams and co. ET, while at that same time, Michael Penix Jr. 5 USC will visit Arizona State at 10:30 p.m. The two biggest Heisman favorites will get chances to add to their resumes in separate late-night games on Saturday.